As BioNTech’s AI research organization, InstaDeep is leading the AI revolution in biology with breakthroughs like the Nucleotide Transformer[1], ProtBFN[2], and InstaNovo[3]. In the RNA group, we develop AI for BioNTech’s core technology, the foundation of the first Covid vaccine[4] and the world’s leading personalized cancer immunotherapy program[5].
Join us to be a part of the AI revolution and contribute to life-changing treatments!
In the BioAI department, we advance the boundaries of healthcare and medical science through a combination of biology and artificial intelligence expertise. Notably, we are developing the next-generation vaccines, as well as pharmaceutics for cancer treatment and prevention and therapy of infectious diseases. By joining us, you will contribute to this effort in collaboration with scientists, engineers and biologists from both InstaDeep and BioNTech.
In this position, you will implement scientific algorithms, particularly with a focus on RNA-related research and development. You will also provide software support for BioAI projects, contributing to technical aspects such as software engineering, optimisation algorithms, automation, and deployment. Your work will significantly contribute towards advancing our understanding of biological systems and improving clinical outcomes.
Responsibilities
- Design, develop, and optimize software implementations of scientific algorithms, with a focus on RNA-related research and development.
- Develop tools and frameworks to streamline workflows and improve efficiency, while serving as the primary internal point of contact for software design and technical implementation matters.
- Develop high-performance implementations to address computationally intensive tasks.
- Build and maintain robust, maintainable, and modular software systems, with precise documentation.
- Contribute to automation and deployment pipelines to support the efficient execution of BioAI projects.
- Collaborate with researchers and biologists to translate scientific goals into efficient software solutions.
- Utilize DevOps/MLOps practices and cloud-based infrastructures to ensure scalability and reliability.
- Provide clear, well-structured reporting and communication of results and technical designs to internal teams and external collaborators.
Requirements
- A PhD or Master’s degree in a relevant field.
- Extensive programming experience with strong experience in Python.
- Experience developing scientific software (such as for simulations, bioinformatics algorithms, signal processing, etc.).
- Some experience in a lower-level programming language for high-performance implementations (e.g., C++, Rust).
- Proficient in Linux environments and version control systems such as Git.
- CI/CD pipelines or workflows and containerization (Docker).
- Excellent communication skills in English.
- A work permit is needed for the considered location.
Desirable
- Proven track record of contributing to scientific projects, including open-source software contributions or research publications.
- Experience designing and writing software for biochemistry (preferably), biology, or physics-related applications. Experience with RNA science would be especially beneficial.
- Experience mentoring colleagues or providing technical guidance.
- Awareness of and interest in machine learning techniques, though not required for the role.
- Experience an any of the following software engineering areas would be beneficial: High-performance computing techniques, such as parallel or distributed CPU/GPU implementations (e.g., SIMD vectorization, CUDA, Ray).Cloud computing services (e.g., GCP, AWS, Azure).Database design and management.
References
- [1] Nucleotide Transformer: building and evaluating robust foundation models for human genomics (https://www.nature.com/articles/s41592-024-02523-z)
- [2] Protein sequence modelling with Bayesian flow networks (https://www.nature.com/articles/s41467-025-58250-2)
- [3] InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments (https://www.nature.com/articles/s42256-025-01019-5)
- [4] WHO issues its first emergency use validation for a COVID-19 vaccine and emphasizes need for equitable global access (https://www.who.int/news/item/31-12-2020-who-issues-its-first-emergency-use-validation-for-a-covid-19-vaccine-and-emphasizes-need-for-equitable-global-access)
- [5] BioNTech announces strategic partnership with UK Government to provide personalized cancer immunotherapies (https://investors.biontech.de/news-releases/news-release-details/biontech-announces-strategic-partnership-uk-government-provide)
We empower individuals to celebrate their uniqueness here at InstaDeep. Our team comes from all walks of life, and we’re proud to continue to encourage and support applicants from underrepresented groups across the globe. Our commitment to creating an authentic environment comes from our ability to learn and grow from our diversity, and how better to experience this by other than by joining our team?
***Right to work: Please note you will require the legal right to work in the location you are applying for. We don't sponsor Work Visa******Please submit your CV/Resume in English***
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